This course begins with a brief review of some of the areas of probability and statistics needed for applications to bioinformatics problems. Typical problems addressed by bioinformaticians are identifying functionally different parts of a genome, searching DNA or protein databases to find sequences which are functionally similar to a given query sequence, or inferring the relatedness of different species by measuring the similarity of their genomes. The course will cover the mathematical theory behind algorithms commonly used by biologists and also give examples of current research.
Furthermore, in consultation with the course lecturer, students will (i) select a research topic related to this course, and through reading of professional articles, acquire a fundamental knowledge of that topic. (ii) Write a report (2500 word limit) on the selected topic, explaining fundamental concepts and highlight key questions currently researched in the field. (iii) Demonstrate effective oral communication skills by presenting complex concepts to staff and other students in a 20-minute seminar, based on the report, as well as answer 10 minutes of questions.
Note: This course is co-taught with undergraduate students but assessed separately.
Learning Outcomes
Upon successful completion, students will have the knowledge and skills to:
- Explain thoroughly the fundamental concepts of specific topics in bioinformatics and their role in modern mathematics and applied contexts.
- Demonstrate a deep understanding of the mathematical reasoning underlying specific bioinformatics techniques.
- Demonstrate accurate and efficient use of specific bioinformatics techniques.
- Demonstrate an understanding of current research in bioinformatics by effectively communicating the findings of research articles in leading professional journals in a comprehensive written report.
- Demonstrate capacity for original mathematical reasoning in a broader biological context through analysing, proving and explaining concepts from bioinformatics.
- Demonstrate an understanding of the process of developing novel quantitative techniques in biology with reference to specific material in the published scientific literature.
- Effectively communicate complex quantitative biology concepts relating to their peers and academic staff, through oral presentations.
Indicative Assessment
- Assignments (40) [LO 1,2,3]
- Final exam (35) [LO 1,2,3]
- A research project based on a specific example from published scientific literature Regardless of performance on other assessment items, a minimum score of 35% on the research project is required to pass the course. (This is known as a 'course hurdle'.) (25) [LO 4,5,6,7]
The ANU uses Turnitin to enhance student citation and referencing techniques, and to assess assignment submissions as a component of the University's approach to managing Academic Integrity. While the use of Turnitin is not mandatory, the ANU highly recommends Turnitin is used by both teaching staff and students. For additional information regarding Turnitin please visit the ANU Online website.
Workload
The expected workload will consist of approximately 130 hours throughout the semester including:
- Face-to face component which will consist of 3 x 1 hour Lectures and 1 x 1 hour workshop per week.
- Approximately 82 hours of self-directed study which will include listening/viewing the online lectures, preparation for the weekly lectures, workshops and other assessment tasks.
Inherent Requirements
No specific inherent requirements have been identified for this course.
Requisite and Incompatibility
You will need to contact the Mathematical Sciences Institute to request a permission code to enrol in this course.
Prescribed Texts
None.
Assumed Knowledge
Bachelor of Science or equivalent with a major in either mathematics, or statistics or physics with relevant experience or academic achievement.
Fees
Tuition fees are for the academic year indicated at the top of the page.
Commonwealth Support (CSP) Students
If you have been offered a Commonwealth supported place, your fees are set by the Australian Government for each course. At ANU 1 EFTSL is 48 units (normally 8 x 6-unit courses). More information about your student contribution amount for each course at Fees.
- Student Contribution Band:
- 2
- Unit value:
- 6 units
If you are a domestic graduate coursework student with a Domestic Tuition Fee (DTF) place or international student you will be required to pay course tuition fees (see below). Course tuition fees are indexed annually. Further information for domestic and international students about tuition and other fees can be found at Fees.
Where there is a unit range displayed for this course, not all unit options below may be available.
| Units | EFTSL |
|---|---|
| 6.00 | 0.12500 |
Course fees
- Domestic fee paying students
| Year | Fee |
|---|---|
| 2025 | $4680 |
- International fee paying students
| Year | Fee |
|---|---|
| 2025 | $6720 |
Offerings, Dates and Class Summary Links
ANU utilises MyTimetable to enable students to view the timetable for their enrolled courses, browse, then self-allocate to small teaching activities / tutorials so they can better plan their time. Find out more on the Timetable webpage.
Class summaries, if available, can be accessed by clicking on the View link for the relevant class number.
First Semester
| Class number | Class start date | Last day to enrol | Census date | Class end date | Mode Of Delivery | Class Summary |
|---|---|---|---|---|---|---|
| 2615 | 17 Feb 2025 | 24 Feb 2025 | 31 Mar 2025 | 23 May 2025 | In Person | View |